Expression of mRNA for muscarinic receptor subtypes and neuronal nicotinic receptor subunits in human mononuclear leukocytes
نویسندگان
چکیده
منابع مشابه
MUSCARINIC RECEPTOR SUBTYPES IN SMOOTH MUSCLE FROM THE BODY OF HUMAN STOMACH
Up to date, there are four pharmacologically characterized subtypes of muscarinic receptors (M1, M2, M3 and M4). In our study we have investigated muscarinic receptor subtypes in smooth muscle layers of human stomach. Isolated preparations of longitudinal and circular muscle layers from human stomach were used. Acetylcholine, bethanechol, carbachol, pilocarpine and AHR -602 produced concen...
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Muscarinic receptor subtypes in the airways appear to subserve different physiological functions. M1-receptors facilitate neurotransmission through parasympathetic ganglia and enhance cholinergic reflexes, but are also localized to alveolar walls. M2-receptors act as autoreceptors on post-ganglionic cholinergic nerves and inhibit acetylcholine release. There is some evidence that they may be de...
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Leptin is secreted mainly by fat, which is involved in energy metabolism and reproduction. Leptin and itsreceptor (Ob-R) have been detected in human spermatozoa and testis, thus it can be concluded leptin involves in male physiology. The goal of this study was determination of the presence of leptin receptor mRNA in the ram testis, epididymis and spermatozoa by reverse transcription polymerase ...
متن کاملmuscarinic receptor subtypes in smooth muscle from the body of human stomach
up to date, there are four pharmacologically characterized subtypes of muscarinic receptors (m1, m2, m3 and m4). in our study we have investigated muscarinic receptor subtypes in smooth muscle layers of human stomach. isolated preparations of longitudinal and circular muscle layers from human stomach were used. acetylcholine, bethanechol, carbachol, pilocarpine and ahr -602 produced concentrati...
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Acting through nicotinic acetylcholine receptors (nAChRs), acetylcholine plays an important role in retinal development and the formation of retinal connections to target tissues, but very little is known about the nAChR subtypes expressed in vertebrate retina during neuronal development. We used immunoprecipitation and [3H]epibatidine binding to study the expression of chick retina alpha-bunga...
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ژورنال
عنوان ژورنال: Japanese Journal of Pharmacology
سال: 1999
ISSN: 0021-5198
DOI: 10.1016/s0021-5198(19)34214-3